Engineering static and dynamic control of synthetic pathways.

Holtz, William J; Keasling, Jay D · Cell · 2010

basic_science · Level V

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Abstract

Maximizing the production of a desired small molecule is one of the primary goals in metabolic engineering. Recent advances in the nascent field of synthetic biology have increased the predictability of small-molecule production in engineered cells growing under constant conditions. The next frontier is to create synthetic pathways that adapt to changing environments.

Medical subject headings