MicroTUB(B3)ules and brain development.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20085703.
- Also identified by DOI 10.1016/j.cell.2009.12.038.
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Abstract
The microtubule network is crucial for the developing nervous system, and mutations in tubulin-encoding genes disrupt neuronal migration. Tischfield et al. (2010) now report that mutations in the tubulin-encoding gene TUBB3 have a striking impact on microtubule dynamics in neurons, resulting in a diverse set of disease symptoms.
Medical subject headings
- Brain
- Microtubules
- Tubulin