Failure of resolution of portal fibrosis during omega-3 fatty acid lipid emulsion therapy in two patients with irreversible intestinal failure.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 20105644.
- Also identified by DOI 10.1016/j.jpeds.2009.08.033.
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Abstract
Parenteral omega-3 fatty acid lipid emulsions have been evaluated for their potential role in reversing intestinal failure-associated liver disease. We report our experience using Omegaven in 2 patients with irreversible intestinal failure and intestinal failure-associated liver disease. Despite biochemical and histologic improvement in cholestasis, both patients had persisting, significant portal fibrosis on liver biopsy.
Medical subject headings
- Fat Emulsions, Intravenous
- Fatty Acids, Omega-3
- Hirschsprung Disease
- Intestinal Diseases
- Liver Cirrhosis, Biliary
- Parenteral Nutrition