Mycobacterial hand infections occurring postoperatively in patients treated with tumor necrosis factor-alpha inhibitors for inflammatory arthritis: report of three cases.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 20117311.
- Also identified by DOI 10.1016/j.jhsa.2009.09.018.
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Abstract
Tumor necrosis factor-alpha inhibitors are potent anti-rheumatic drugs, but there is evidence that the high level of immunosuppression they provide may also lead to a higher risk of infections. At our institution, 3 patients with inflammatory arthritis treated with tumor necrosis factor-alpha inhibitors developed mycobacterial soft tissue infections after routine hand surgery. All 3 patients required multiple surgical procedures, inpatient hospitalizations, and prolonged antibiotic multidrug therapy to clear the infections.
Medical subject headings
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Azithromycin
- Hand
- Mycobacterium Infections
- Tenosynovitis
- Tumor Necrosis Factor-alpha
Anatomy
- hand