Epidemiology: Interpreting studies of interactions between RA risk factors.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 20125172.
- Also identified by DOI 10.1038/nrrheum.2009.276.
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Abstract
Interactions between HLA and PTPN22 genotypes and smoking have been implicated in overall susceptibility to rheumatoid arthritis as well as the incidence of particular disease phenotypes in case-control and case-only studies. As recent epidemiological evidence shows, deciphering these interactions demands consideration of the analytical approach used.
Medical subject headings
- Arthritis, Rheumatoid
- HLA-DR Antigens
- Protein Tyrosine Phosphatase, Non-Receptor Type 22
- Smoking