Pre-morbid adjustment and personality in psychosis. Effects of sex and diagnosis.
case_control · Level III
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Abstract
Pre-morbid schizoid and schizotypal traits and social adjustment were assessed blind to diagnosis by interviewing the mothers of 73 consecutively admitted patients with DSM-III schizophrenia or affective psychosis. Analysis of factors associated with pre-morbid deficits showed a highly significant interaction of diagnosis with sex, such that schizophrenic men showed much greater pre-morbid impairment than either schizophrenic women or men with affective disorder. Poor pre-morbid adjustment predicted an early age at first admission. The results can be explained by a neurodevelopmental disorder in some schizophrenic males.
Medical subject headings
- Affective Disorders, Psychotic
- Schizoid Personality Disorder
- Schizophrenia
- Schizotypal Personality Disorder
- Social Adjustment