Evidence for neuronal expression of functional Fc (epsilon and gamma) receptors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20132972.
- Also identified by DOI 10.1016/j.jaci.2009.10.054 and PMC identifier 2839037.
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Abstract
We report that neurons express functional Fc receptors (including FcεR1), that can be activated by antigen, transmit signals along nerve fibers <i>in vitro</i> and <i>in vivo</i>. These results open new avenues of investigation in neurogenic inflammation and allergic diseases.
Medical subject headings
- Cell Communication
- Neurons
- Receptors, IgE
- Receptors, IgG
- Signal Transduction