Duct tape for broken chromosomes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20141831.
- Also identified by DOI 10.1016/j.cell.2010.01.005.
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Abstract
A cell undergoing mitosis is presented with a potentially catastrophic situation when a DNA double-strand break creates a chromosome fragment that lacks connection to a centromere. Royou et al. (2010) now reveal that this cellular crisis is averted in fruit fly neuroblasts by thin chromatin tethers that hold on to the ends of the broken chromosomes.
Medical subject headings
- Centromere
- Chromosomes
- Drosophila