Treating obesity? It's in the bag!
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20142097.
- Also identified by DOI 10.1016/j.cmet.2010.01.006.
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Abstract
BRS-3 is an orphan G protein coupled receptor highly expressed in the brain. Pharmacological studies in this issue (Guan et al., 2010) further support a role for this receptor in energy homeostasis and show that the BRS-3 agonist Bag-1 effectively causes weight loss by decreasing food intake and increasing metabolic rate.