Nups take leave of the nuclear envelope to regulate transcription.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20144754.
- Also identified by DOI 10.1016/j.cell.2010.01.036 and PMC identifier 3040115.
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Abstract
Although components of the nuclear pore complex have been implicated in gene regulation independent of their role at the nuclear envelope, the evidence so far has been indirect. Capelson et al. (2010) and Kalverda et al. (2010) now reveal that certain nucleoporins are actively involved in transcription inside the nucleoplasm of Drosophila cells.
Medical subject headings
- Drosophila
- Gene Expression Regulation
- Nuclear Pore Complex Proteins
- Transcription, Genetic