Age-related changes in niche cells influence hematopoietic stem cell function.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20144780.
- Also identified by DOI 10.1016/j.stem.2010.01.008.
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Abstract
In a recent issue of Nature, Mayack et al. (2010) use young and old parabiotic mice to show that systemic signals from the young parabiont rejuvenate hematopoietic stem cell function via the microenvironmental niche.