A dominant role of the hair follicle stem cell niche in regulating melanocyte stemness.

Blanpain, Cédric; Sotiropoulou, Panagiota A · Cell Stem Cell · 2010

basic_science · Level V

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Abstract

Melanocyte and hair follicle bulge stem cells share a common niche. In this issue of Cell Stem Cell, Nishimura et al. (2010) show that hair follicle stem cells, by expressing high levels of TGF-beta2, regulate the quiescence, the stemness, and the long-term renewal of melanocyte stem cells.