NO Signals from the Cancer Stem Cell Niche.

Seoane, Joan · Cell Stem Cell · 2010

editorial · Level V

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Abstract

Characterization of signaling pathways that control cancer stem cells may lead to more effective treatments against cancer. In this issue of Cell Stem Cell, a study by Charles et al. (2010) identifies the NO and Notch pathways as important regulators of the perivascular niche of cancer stem cells in glioma.