Iodine-125 interstitial implants as salvage therapy for recurrent gynecologic malignancies.

Sharma, S K; Forgione, H; Isaacs, J H · Cancer · 1991

case_series · Level IV

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Abstract

Twenty-one patients with the diagnosis of recurrent gynecologic pelvic malignancy from various primary sites were treated with iodine-125 (I-125) interstitial implants. Eighteen of these patients had been treated with a combination of surgery and radiation therapy for their primary malignancies and 90% had responded. Seventy-five percent had complete local responses. The overall survival time, volume-response relationship, and complications are discussed and the radioresponse of various histologic types is presented.

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