Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20162227.
- Also identified by DOI 10.1039/b924816a and PMC identifier 4538600.
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Abstract
A method for integrating porous polymer membranes such as polycarbonate, polyethersulfone and polyethylene terephthalate to microfluidic devices is described. The use of 3-aminopropyltriethoxysilane as a chemical crosslinking agent was extended to integrate membranes with PDMS and glass microfluidic channels. A strong, irreversible bond between the membranes and microfluidic structure was achieved. The bonding strength in the APTES treated devices was significantly greater than in devices fabricated using either a PDMS "glue" or two-part epoxy bonding method. Evaluation of a filtering microdevice and the pore structure via SEM indicates the APTES conjugation does not significantly alter the membrane transport function and pore morphology.
Medical subject headings
- Dimethylpolysiloxanes
- Glass
- Membranes, Artificial
- Micro-Electrical-Mechanical Systems
- Nanostructures