Recombinant human bone morphogenetic protein 2-induced heterotopic ossification of the retroperitoneum, psoas muscle, pelvis and abdominal wall following lumbar spinal fusion.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 20162273.
- Also identified by DOI 10.1007/s00256-010-0890-8.
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Abstract
A 45-year-old man presented with vertebral collapse at L5 as an initial manifestation of multiple myeloma and underwent spinal fusion surgery using recombinant human bone morphogenetic protein-2 (rhBMP-2). Subsequent computed tomography (CT) scans and X-rays revealed heterotopic ossification of the left psoas muscle, pelvis, and anterior abdominal wall. While the occurrence of heterotopic ossification has previously been reported when rhBMP-2 has been used for spinal fusion surgery, this case demonstrates that it can occur to a much greater degree than previously seen.
Medical subject headings
- Bone Morphogenetic Protein 2
- Muscular Diseases
- Ossification, Heterotopic
- Pelvis
- Radiography, Abdominal
- Recombinant Proteins
- Spinal Fusion
Anatomy
- lumbar spine
- pelvis