Radiation dose-volume effects in the heart.
systematic_review · Level I
Where this comes from
- Record sourced from PubMed, PMID 20171522.
- Also identified by DOI 10.1016/j.ijrobp.2009.04.093.
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Abstract
The literature is reviewed to identify the main clinical and dose-volume predictors for acute and late radiation-induced heart disease. A clear quantitative dose and/or volume dependence for most cardiac toxicity has not yet been shown, primarily because of the scarcity of the data. Several clinical factors, such as age, comorbidities and doxorubicin use, appear to increase the risk of injury. The existing dose-volume data is presented, as well as suggestions for future investigations to better define radiation-induced cardiac injury.
Medical subject headings
- Heart
- Heart Diseases
- Radiation Injuries