IMRT-based optimization approaches for volumetric modulated single arc radiotherapy planning.

Crijns, Wouter; Budiharto, Tom; Defraene, Gilles; Verstraete, Jan; Depuydt, Tom; Haustermans, Karin; Van den Heuvel, Frank · Radiother Oncol · 2010

prospective_cohort · Level II

Where this comes from

Abstract

This paper reports on an evaluation of 5 RapidArc optimization approaches vs IMRT. This study includes 11 patients with adenocarcinoma of the prostate. Rectal Normal Tissue Complication Probability is used as a constraint in a dose escalation. RapidArc rectal NTCP's are lower than those of IMRT (p = 0.007). This allows a mean dose escalation of 2.1 Gy([0.7 Gy,3.5 Gy]).

Medical subject headings