Drug allergy.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20176256.
- Also identified by DOI 10.1016/j.jaci.2009.10.028.
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Abstract
Drug allergy is one type of adverse reaction to drugs and encompasses a spectrum of hypersensitivity reactions with heterogeneous mechanisms and clinical presentations. A thorough history is essential to the management of drug allergy. Laboratory testing has a very limited role in the management of drug allergy. Graded dose challenges and procedures to induce drug tolerance might be required in patients with drug allergy when there is a definite need for a particular agent. Management of reactions to specific agents, including beta-lactam antibiotics, sulfonamides, local anesthetics, radiocontrast media, angiotensin-converting enzyme inhibitors, nonsteroidal anti-inflammatory drugs, and biologic modifiers, will be discussed in further detail.
Medical subject headings
- Drug Hypersensitivity
- Drug-Related Side Effects and Adverse Reactions