Lin28: A microRNA regulator with a macro role.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20178735.
- Also identified by DOI 10.1016/j.cell.2010.02.007.
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Abstract
Lin28, a highly conserved RNA-binding protein, has emerged as a modulator of the processing of the let-7 microRNA. This role for Lin28 has important implications for our mechanistic understanding of pluripotency, the timing of development, and oncogenesis.
Medical subject headings
- MicroRNAs
- Protein Processing, Post-Translational
- RNA-Binding Proteins