Modulating tumor vasculature through signaling inhibition to improve cytotoxic therapy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20179191.
- Also identified by DOI 10.1158/0008-5472.CAN-09-3615 and PMC identifier 2840203.
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Abstract
The tumor microenvironment is a key factor in cancer treatment response. Recent work has shown that changes in the tumor vasculature can be achieved by inhibiting tumor cell signaling, resulting in enhanced tumor oxygenation. These changes could promote responses to both chemo- and radiation therapy.
Medical subject headings
- Neoplasms