Imipramine treatment of methadone maintenance patients with affective disorder and illicit drug use.
case_series · Level IV
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- Record sourced from PubMed, PMID 2018172.
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Abstract
Of 17 consecutive patients receiving methadone maintenance treatment who had primary or chronic depression, nine (53%) improved in both mood and drug abuse after imipramine treatment. This finding suggests a potential for helping such dual-diagnosis patients reduce drug abuse and associated risk for HIV. Further controlled trials are warranted.
Medical subject headings
- Depressive Disorder
- Imipramine
- Methadone
- Substance-Related Disorders