Better nephrology for mice--and man.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 20186162.
- Also identified by DOI 10.1038/ki.2009.544.
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Abstract
The use of creatinine to estimate glomerular filtration rate in patients is prone to well-described artifacts that impact its interpretation. Eisner et al. now show that the impact of creatinine secretion on creatinine clearance is even larger in mice than in humans, raising questions regarding the utility of creatinine for measuring glomerular filtration rate in mice.
Medical subject headings
- Kidney Function Tests
- Nephrology