HLA-D antigens and Paget's disease of bone.
case_control · Level III
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- Record sourced from PubMed, PMID 2019065.
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Abstract
HLA-A, -B, -C, -DR, and -DQ antigens were determined in 25 Ashkenazi Jews with Paget's disease of bone. HLA-DR2 was more frequent in the Pagetic patients compared with 57 healthy controls of the same ethnic origin. This finding concurs with a previous report and raises the possibility that HLA-DR2 may be associated with Paget's disease of bone, probably by predisposing the bone cells to viral infection.
Medical subject headings
- HLA-D Antigens
- Osteitis Deformans