Possible neuropsychiatric reaction to high-dose oseltamivir during acute 2009 H1N1 influenza A infection.

Nakamura, Kenta; Schwartz, Brian S; Lindegårdh, Niklas; Keh, Chris; Guglielmo, B Joseph · Clin Infect Dis · 2010

case_report · Level V

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Abstract

The safety of high-dose oseltamivir during treatment of 2009 H1N1 influenza A infection for critically ill patients is unknown. Here we report on a case patient with severe, delayed-onset neuropsychiatric symptoms after administration of high-dose oseltamivir. Clinicians should be vigilant to the possible increased risk of complications associated with high-dose oseltamivir therapy for 2009 H1N1 influenza A infection.

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