Vaccine-associated herpes zoster ophthalmicus [correction of opthalmicus] and encephalitis in an immunocompetent child.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 20194287.
- Also identified by DOI 10.1542/peds.2009-2633.
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Abstract
Varicella-zoster virus vaccine has diminished the consequences of chicken pox in terms of health and economical burden. The increasing number of doses administered worldwide has revealed rare but important adverse effects that had not occurred during clinical trials. We report here the case of an immunocompetent 3(1/2)-year-old girl who developed encephalitis and herpes zoster opthalmicus 20 months after her immunization with varicella-zoster virus vaccine. Molecular analysis confirmed the vaccine strain as the causative agent. After an intravenous course with acyclovir, the child made a full recovery with no neurologic sequelae.
Medical subject headings
- Encephalitis, Varicella Zoster
- Herpes Zoster Ophthalmicus
- Herpes Zoster Vaccine
- Immunocompetence