Visualization of multiple alignments, phylogenies and gene family evolution.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20195253.
- Also identified by DOI 10.1038/nmeth.1434.
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Abstract
Software for visualizing sequence alignments and trees are essential tools for life scientists. In this review, we describe the major features and capabilities of a selection of stand-alone and web-based applications useful when investigating the function and evolution of a gene family. These range from simple viewers, to systems that provide sophisticated editing and analysis functions. We conclude with a discussion of the challenges that these tools now face due to the flood of next generation sequence data and the increasingly complex network of bioinformatics information sources.
Medical subject headings
- Biological Evolution
- Multigene Family
- Phylogeny
- Sequence Alignment