Visualization of macromolecular structures.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20195256.
- Also identified by DOI 10.1038/nmeth.1427 and PMC identifier 7097155.
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Abstract
Structural biology is rapidly accumulating a wealth of detailed information about protein function, binding sites, RNA, large assemblies and molecular motions. These data are increasingly of interest to a broader community of life scientists, not just structural experts. Visualization is a primary means for accessing and using these data, yet visualization is also a stumbling block that prevents many life scientists from benefiting from three-dimensional structural data. In this review, we focus on key biological questions where visualizing three-dimensional structures can provide insight and describe available methods and tools.
Medical subject headings
- Image Processing, Computer-Assisted
- Macromolecular Substances