Previews. Crossing boundaries: direct programming of fibroblasts into neurons.
editorial · Level V
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- Record sourced from PubMed, PMID 20207219.
- Also identified by DOI 10.1016/j.stem.2010.02.004.
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Abstract
In a recent paper in Nature, Vierbuchen et al. (2010) show that fibroblasts can be directly converted into functional neurons by defined factors. This finding sheds new light on the biology underlying cell-fate restrictions and might offer a new avenue for studying neurological diseases.