Previews. Niche today, gone tomorrow--progenitors create short-lived niche for stem cell specification.

Issigonis, Melanie; Matunis, Erika · Cell Stem Cell · 2010

review · Level V

Where this comes from

Abstract

Establishing tissue-specific adult stem cells during organogenesis is important for maintenance of tissue homeostasis throughout the lifetime of the organism. In a recent study in Science, Mathur et al. (2010) describe how progenitor cells in the Drosophila larval midgut create a temporary niche to maintain stem cell fate during development.