What have we learnt from hyperbaric oxygen?
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 2020772.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The 15 randomised controlled clinical trials of hyperbaric oxygen in radiotherapy yielded three with highly significant benefit and six with useful margins not reaching statistical significance. The increase in tumour control was partly negated by an increase in normal tissue effect. Now simple carbogen breathing in animal tumour models has shown high efficiency and there is the potential for its use in man as a simple means of hypoxic cell radiosensitization.
Medical subject headings
- Cell Hypoxia
- Hyperbaric Oxygenation
- Neoplasms