Serologic response to hepatitis B vaccination in HIV-Infected patients with isolated positivity for antibodies to hepatitis B core antigen.

Chakvetadze, Catherine; Bani-Sadr, Firouzé; Le Pendeven, Catherine; Lescure, François-Xavier; Fontaine, Camille; Galperine, Tatiana; Slama, Laurence; Bonnard, Philippe et al. · Clin Infect Dis · 2010

prospective_cohort · Level II

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Abstract

We assessed the safety and immunogenicity of hepatitis B vaccination among 40 human immunodeficiency virus-infected patients with isolated positivity for antibodies to hepatitis B core antigen. No baseline factors were found to be predictive of an anamnestic response, which occurred in 32.5% of the patients. The overall response rate among patients without an anamnestic response was 74.0% after 3-6 vaccine doses.

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