TB: screening for responses to a vile visitor.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 20211131.
- Also identified by DOI 10.1016/j.cell.2010.02.030.
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Abstract
Mycobacteria, the pathogens that cause tuberculosis and leprosy, establish long-term infections in host macrophages. Recent studies, including two genetic screens reported in this issue of Cell (Kumar et al., 2010; Tobin et al., 2010), reveal that virulent mycobacteria evade the host immune system by stimulating production of anti-inflammatory molecules and inhibiting autophagy.
Medical subject headings
- Macrophages
- Mycobacterium tuberculosis
- Tuberculosis