Effect on mydriasis of modifying the volume of phenylephrine drops.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 2021589.
- Also identified by PMC identifier 1042326.
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Abstract
The cardiovascular effects of topically administered phenylephrine 10% are well known and can be minimised by reducing the concentration of drops administered. By modifying the dimensions of the dropper tip we reduced the volume of the drops administered, and therefore the total dose of phenylephrine, without altering the concentration. No difference in the mydriasis produced by drops of small and normal volume could be detected. Since a smaller dose of phenylephrine is administered with smaller drops, the risk of systemic side effects could be reduced by modifying the tips of eyedroppers.
Medical subject headings
- Ophthalmic Solutions
- Phenylephrine
- Pupil