Patterned multiplex pathogen DNA detection by Au particle-on-wire SERS sensor.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20222740.
- Also identified by DOI 10.1021/nl1000086.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A Au particle-on-wire system that can be used as a specific, sensitive, and multiplex DNA sensor is developed. A pattern formed by multiple Au nanowire sensors provides positional address and identification for each sensor. By using this system, multiplex sensing of target DNAs was possible in a quantitative manner with a detection limit of 10 pM. Target DNAs from reference bacteria and clinical isolates were successfully identified by this sensor system, enabling diagnostics for infectious diseases.
Medical subject headings
- Biosensing Techniques
- DNA, Bacterial
- Gold
- Metal Nanoparticles
- Nanotechnology
- Nanowires