TiSGeD: a database for tissue-specific genes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 20223836.
- Also identified by DOI 10.1093/bioinformatics/btq109 and PMC identifier 2859128.
- Licence recorded as CC BY-NC.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The tissue-specific genes are a group of genes whose function and expression are preferred in one or several tissues/cell types. Identification of these genes helps better understanding of tissue-gene relationship, etiology and discovery of novel tissue-specific drug targets. In this study, a statistical method is introduced to detect tissue-specific genes from more than 123 125 gene expression profiles over 107 human tissues, 67 mouse tissues and 30 rat tissues. As a result, a novel subject-specialized repository, namely the tissue-specific genes database (TiSGeD), is developed to represent the analyzed results. Auxiliary information of tissue-specific genes was also collected from biomedical literatures. http://bioinf.xmu.edu.cn/databases/TiSGeD/index.html.
Medical subject headings
- Computational Biology
- Gene Expression Profiling