Booster vaccination after neonatal priming with acellular pertussis vaccine.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 20303444.
- Also identified by DOI 10.1016/j.jpeds.2009.12.019.
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Abstract
After a birth dose of acellular pertussis (aP) and diphtheria (DT)aP-hepatitis B virus (HBV)-inactivated polio vaccine (IPV)/Haemophilus influenza type b (Hib) at 2, 4, and 6 months, a booster dose of DTaP-HBV-IPV/Hib at 12 to 23 months induced strong anti-pertussis booster responses. Thus, neonatal aP priming did not lead to immune tolerance to pertussis antigens. However, it elicited bystander interference on HBV, Hib, and diphtheria responses.
Medical subject headings
- Immunization, Secondary
- Pertussis Vaccine
- Vaccination
- Whooping Cough