Non-immune goiter and hypothyroidism in a 19-week fetus: a plea for conservative treatment.

Stoppa-Vaucher, Sophie; Francoeur, Diane; Grignon, Andrée; Alos, Nathalie; Pohlenz, Joachim; Hermanns, Pia; Van Vliet, Guy; Deladoëy, Johnny · J Pediatr · 2010

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Abstract

Hypothyroidism was documented by cordocentesis at 19 weeks in a fetus with non-immune goiter. Intra-amniotic thyroxine was injected at 25 weeks when amniotic fluid volume increased. Psychomotor outcome was normal. We argue that intra-amniotic thyroxine should not be used to treat the hypothyroidism but only to correct the development of polyhydramnios.

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