Anti-IgE therapy results in decreased myeloid dendritic cells in asthmatic airways.

Chand, Hitendra S; Schuyler, Mark; Joste, Nancy; Hensler, Charlene; Tesfaigzi, Yohannes; Masten, Barbara; Schrader, Ron; Lipscomb, Mary F · J Allergy Clin Immunol · 2010

case_series · Level IV

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Abstract

Anti-IgE treatment of intermittent to mild-persistent asthma in a cohort of seven volunteers resulted in improved allergen-induced airway hyperreactivity and a significant reduction in the number of airway myeloid dendritic cells.

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