Epithelial-mesenchymal transitions and hepatocarcinogenesis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 20335655.
- Also identified by DOI 10.1172/JCI42615 and PMC identifier 2846072.
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Abstract
Epithelial-mesenchymal transitions (EMTs) are believed to play a role in invasion and metastasis of many types of tumors. In this issue of the JCI, Chen et al. show that a gene that has been associated with aggressive biology in hepatocellular carcinomas initiates a molecular cascade that results in EMT.
Medical subject headings
- Carcinoma, Hepatocellular
- Epithelial Cells
- Liver Neoplasms
- Mesoderm