Urinary liver fatty acid-binding protein: another novel biomarker of acute kidney injury.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20354549.
- Also identified by DOI 10.1038/ki.2010.5.
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Abstract
Liver fatty acid-binding protein (L-FABP) binds selectively to intracellular free unsaturated fatty acids and lipid peroxidation products during hypoxic tissue injury. Urinary L-FABP is a potential biomarker for the detection and assessment of acute kidney injury (AKI). Ferguson et al. have demonstrated in a cross-sectional study that urinary L-FABP is an excellent biomarker of AKI and may be useful in predicting dialysis-free survival. This study did not assess utility for early diagnosis of AKI.
Medical subject headings
- Acute Kidney Injury
- Fatty Acid-Binding Proteins
- Kidney
- Urinary Tract