Elevation of plasma concentrations of haloperidol after the addition of fluoxetine.
case_series · Level IV
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- Record sourced from PubMed, PMID 2035723.
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Abstract
Fluoxetine (20 mg/day) was added for 7-10 days to stable doses of haloperidol given to eight psychotic patients. Mean plasma concentrations of haloperidol were elevated by 20% (p less than 0.05), but extrapyramidal side effects did not increase appreciably, indicating a relatively minor interaction between these agents.
Medical subject headings
- Fluoxetine
- Haloperidol