Can animal models of disease reliably inform human studies?

van der Worp, H Bart; Howells, David W; Sena, Emily S; Porritt, Michelle J; Rewell, Sarah; O'Collins, Victoria; Macleod, Malcolm R · PLoS Med · 2010

review · Level V

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Abstract

H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials.

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