Cycling toward elimination of leukemic stem cells.
editorial · Level V
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- Record sourced from PubMed, PMID 20362532.
- Also identified by DOI 10.1016/j.stem.2010.03.008.
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Abstract
In two recent articles in Science Translational Medicine and Nature Biotechnology, Saito et al. (2010) identify a molecular signature of acute myeloid leukemia (AML) stem cells and demonstrate that quiescent AML stem cells become sensitized to chemotherapy after G-CSF stimulation.