Computational genetic mapping in mice: the ship has sailed.

Zheng, Ming; Shafer, Steve; Liao, Guochun; Liu, Hong-Hsing; Peltz, Gary · Sci Transl Med · 2009

review · Level V

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Abstract

Computational haplotype-based genetic mapping can be used to discover new biological mechanisms, disease-related pathways, and unexpected uses for existing drugs. Here we discuss the benefits and limitations of this methodology, its impact on translational medicine, and its future course.

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