Optogenetics 3.0.

Liu, Xu; Tonegawa, Susumu · Cell · 2010

basic_science · Level V

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Abstract

Optogenetic methods use light to modulate the activities of target cells in vivo. By improving inter- and intracellular trafficking of light-sensitive switch proteins called opsins, Gradinaru et al. (2010) have developed a new generation of optogenetic tools capable of regulating the activity of targeted neurons with exquisite precision and efficiency.