Pregnancy increases the growth rates of World Health Organization grade II gliomas.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 20373352.
- Also identified by DOI 10.1002/ana.21888.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Twelve pregnancies in 11 adult women harboring World Health Organization (WHO) grade II gliomas (GIIGs) prior to pregnancy were reviewed to address whether pregnancy affects tumor growth using a quantitative approach of the radiological velocity of diametric expansion (VDE) on successive magnetic resonance images. VDE was significantly increased during pregnancy as compared to prepregnancy (p < 0.001) and to postdelivery (p = 0.012) periods. Pregnancy increases the radiological growth rates of GIIGs. An increase in seizure frequency was observed concomitantly in 40% of cases and further oncological treatment was started after delivery in 25% of cases.
Medical subject headings
- Brain
- Brain Neoplasms
- Glioma
- Neoplasm Invasiveness
- Pregnancy Complications, Neoplastic