Fighting back: peptidomimetics as a new weapon in the battle against antibiotic resistance.
Level V
Where this comes from
- Record sourced from PubMed, PMID 20374995.
- Also identified by DOI 10.1126/scitranslmed.3000889.
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Abstract
The discovery, development, and clinical exploitation of antibiotics with new mechanisms of action is a top priority in the battle against untreatable infectious diseases. Peptidomimetics can successfully control infections caused by multidrug-resistant pathogens. This Perspective discusses findings in a recent Science paper on a member of this class of therapeutic agents that targets bacterial outer-membrane synthesis.
Medical subject headings
- Anti-Bacterial Agents
- Antimicrobial Cationic Peptides
- Drug Resistance, Multiple, Bacterial