Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20392477.
- Also identified by DOI 10.1016/j.jaci.2010.01.055 and PMC identifier 2902687.
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Abstract
Eosinophils are multifunctional leukocytes that increase in various tissues in patients with a variety of disorders. Locally, they can be involved in the initiation and propagation of diverse inflammatory responses. In this review the clinical association of eosinophils with diseases of the skin, lung, and gastrointestinal tract is summarized. An approach to determining the causal role of eosinophils in these diseases is presented. Recent findings concerning molecular diagnosis, cause, and treatment are discussed.
Medical subject headings
- Eosinophilia
- Eosinophils
- Gastrointestinal Diseases
- Pulmonary Eosinophilia
- Skin Diseases