Aggressive lymphomas.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 20393178.
- Also identified by DOI 10.1056/NEJMra0807082 and PMC identifier 7316377.
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Abstract
Genomewide molecular profiling has revealed new subtypes of lymphoma that originate from lymphocytes that differ in developmental stage and that use distinct oncogenic programs, yet are indistinguishable under the microscope. In this review, we discuss recent progress in the molecular genetics of aggressive lymphomas and focus on the most common form of this disease, diffuse large-B-cell lymphoma, which accounts for 30 to 40% of newly diagnosed lymphomas.
Medical subject headings
- B-Lymphocytes
- Lymphoma, Large B-Cell, Diffuse